Recovery

APPLICATION PURPOSE

To understand product losses in continuous operation in MEGATRON® line. 

CHALLENGES

• Pilot plant operations.
• Process stability
• Material dependency
  

HOW DID WE ACHIEVE IT?

One of the biggest challenges that all industries are facing nowadays is improving the product quality and increasing operational safety while reducing costs and achieving a sustainable process. To accomplish such a challenge, reduction of product losses is an important task ¹ that is aligned with the Sustainable Development Goal (SDG) 12 (Responsible consumption and production) by contributing with the reduction on waste generation².

Product loss can occur due to unpredictable production stops, problems during intermediate tank storage and planning decisions, but also due to equipment design and piping length. It is at this point where Kinematica’s state-of-the-art technology can contribute³.

THE KINEMATICA SOLUTION

MEGATRON® MT-MM is Kinematica’s solution to ensure not only an efficient process with smaller particle / droplet sizes in inline processes, but also product recovery up to 99% due to the compact design of the working chambers that allows complete discharge!

Would you like more information? Please contact us a science@kinematica.ch

¹ Yang, Y., Ahmed, B., Mitchell, C., Quon, J. L., Siddique, H., Houson, I., Florence, A. J., & Papageorgiou, C. D. (2021). Investigation of Wet Milling and Indirect Ultrasound as Means for Controlling Nucleation in the Continuous Crystallization of an Active Pharmaceutical Ingredient. Organic Process Research & Development, 25(9), 2119–2132. https://doi.org/10.1021/acs.oprd.1c00209

² Engstrom, J., Wang, C., Lai, C., & Sweeney, J. (2013). Introduction of a new scaling approach for particle size reduction in toothed rotor-stator wet mills. International Journal of Pharmaceutics, 456(2), 261–268.

³ SOPAT. (n.d.). INDUSTRIES & APPLICATIONS: Pharma & Biochemistry. INDUSTRIES & APPLICATIONS: Pharma & Biochemistry. Retrieved September 14, 2023, from https://www.sopat.de/en/industries-applications/pharma-biochemistry/